In a new review, some F.D.A. scientists and others say boosters aren’t needed for the general population.

COVID-19 vaccines work so well that most people don’t yet need a booster, an all-star panel of scientists from around the world said in a review that’s likely to fuel the debate over whether to use them.

Governments would be better served to focus on immunizing the unvaccinated and to wait for more data on which boosters, and at what doses, would be most effective, the authors, who included two prominent U.S. Food and Drug Administration experts, argued in the medical journal The Lancet. They based their assessment on a wide range of real-world observational studies as well as data from clinical trials before the vaccines were approved.

“None of the studies has provided credible evidence of substantially declining protection against severe disease,” the authors wrote. There could also be additional side-effect risks if boosters are introduced too soon or too broadly, they said.


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